Better medicines for children: EU Commission initiative to get best and safest treatments for children Part 3

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Better medicines for children: EU Commission initiative to get best and safest treatments for children Part 3 (Teacher: Michael)

It is also being suggested that specific research funding be allocated in combination with mechanism to ensure that it is dedicated to priority areas for health of European children.

Medicines specifically designed for children are limited to traditional areas, among which routine childhood infections and vaccines to to prevent some serious childhood diseases. Very few treatments, for example, are designed or adapted to treat children with diseases such as cancer, AIDS or cardiac disorders.

Doctors trying to adapt adult treatments to children often face tough dilemma, says EU paper called "Better Medicines for Children". Children, and especially toddlers, are not just small adults. Inadequate dosing information, or calculation errors in adjusting dose can raise risks of adverse reactions (overdose) or ineffective treatment (underdose). However careful calculation, child's metabolism differs from that of adult, and this can affect way particular medicine works.

What is needed are not ad hoc dosing decisions but child-specific designs and testing. Failure to provide this might lead to denial of benefits of therapeutic progress.

The absence of suitable authorised medicinal products to treat diseases in children which have been both tested and assessed is issue that has been of concern for some time, says EU Commission's consultation paper. Individual EU member states, regulators, paediatricians and parents have raised subject in various fora.

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